Developmental Abnormalities Associated with a Ring Chromosome 6

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A human ring D chromosome associated with multiple congenital abnormalities.

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Ring chromosomes are rare chromosomal disorders that usually appear to occur de novo. A ring chromosome forms when due to deletion both ends of chromosome fuse with each other. Depending on the amount of chromosomal deletion, the clinical manifestations may be different. So, ring 18 syndrome is characterized by severe mental growth retardation as well as microcephaly, brain and ocular malformat...

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Severe Anomalies Associated With Ring Chromosome

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Congenital malformations associated with a ring 4 chromosome.

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Multiple congenital anomalies associated with a ring-D chromosome.

Ring chromosomes have now been observed in all except one group of the human karyotype, though, as yet, a syndrome has not been recognized which is characterized by the presence of a ring. Ring chromosomes have been observed in group A (Gordon and Cooke, 1964), in group B (Rohde and Tompkins, 1965), in group C (Lindsten and Tillinger, 1962; Turner et al., 1962; Luers, Struck, and Nevinny-Sticke...

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ژورنال

عنوان ژورنال: Journal of Medical Genetics

سال: 1973

ISSN: 1468-6244

DOI: 10.1136/jmg.10.3.299